Here is information regarding some of the top nonprofit organizations in the USA.

World Vision
According to World Visions website, “We are a Christian humanitarian organization dedicated to working with children, families, and their communities worldwide to reach their full potential by tackling the root causes of poverty and injustice. Working in nearly 100 countries around the world, we serve all people, regardless of religion, race, ethnicity, or gender.”
In addition, “World Vision provides emergency assistance to people and children affected by natural disasters and civil conflict.” They work with communities in an effort to establish lasting solutions to relieve poverty and “advocate for justice on behalf of the poor.”
American Heart Association
The American Heart Association is the nation’s oldest, largest voluntary organization committed to battling cardiovascular diseases and stroke.
Started by six cardiologists in 1924, the organization now has more than 22.5 million volunteers and supporters working endlessly to defeat these diseases. The associations supplies money for innovative research, fights for stronger public health policies and provides lifesaving tools and information to save and enhance peoples’ lives.
Salvation Army
According to The Salvation Army website, the organization, “operates 7,546 centers in communities across the United States. These include food distribution, disaster relief, rehabilitation centers, anti-human trafficking efforts, and a wealth of children’s programs. Our work is funded through kettle donations, corporate contributions, and the sale of goods donated to our Salvation Army Family Stores. Eighty-two cents of every dollar we spend supports our various missions across the country. We are a tax-exempt 501(c)(3) organization, and contributions are deductible for Federal Income Tax Purposes to the extent permitted under Section 170(b)(2) for corporations.”